Document Type

Article

Version

Final Published Version

Publication Title

Coordination Chemistry Reviews

Volume

255

Publication Date

2011

Abstract

The molybdenum cofactor is composed of a molybdenum coordinated by one or two rather complicated ligands known as either molybdopterin or pyranopterin. Pterin is one of a large family of bicyclic N-heterocycles called pteridines. Such molecules are widely found in Nature, having various forms to perform a variety of biological functions. This article describes the basic nomenclature of pterin, their biological roles, structure, chemical synthesis and redox reactivity. In addition, the biosynthesis of pterin sand current models of the molybdenum cofactor are discussed.

DOI

https://doi.org/10.1016/j.ccr.2011.02.010

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